Forensic anthropologist Dr. Temperance Brennan teams up with FBI agent Booth to investigate the famous unsolved murder of a young female Senate intern. Their inquiry leads them to suspect three men: the Senator the intern was having an affair with; a speechwriter who became mentally unstable and stalked her; and the intern’s boyfriend, the senator's aid.

Dr. Brennan and FBI agent Booth investigate the mysterious hanging death of a student at an elite prep school; all signs point to suicide, but their investigation leads them to two students who might be to blame.

Brennan and Booth investigate a case concerning a Middle Eastern diplomat accused of a suicide bombing. Their investigation leads them to suspect that the alleged terrorist was actually murdered and framed for the deadly incident.

Brennan and Booth investigate the case of a man on death row who some believe to be innocent. They manage to dig up new evidence - including two additional murders — which forces them to question the wisdom of the stay-of-execution they have helped grant.

After a human hand is found inside a black bear in Washington State, Brennan travels to a small town in Washington State with Agent Booth to investigate the case which leads them to a murderous cannibal.

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Brennan, Booth, and the others are quarantined in the lab on Christmas after the body of unidentified man is discovered in a bomb shelter.

Brennan and Booth search for a missing eight-year-old boy whose mother was murdered, and whose father is about to testify against a US company that manufactured faulty body armor for use in the war in Iraq.

Brennan and Booth travel to Los Angeles to investigate the murder of a call girl who frequented plastic surgery on her face. Elsewhere, Goodman and Hodgins clash while trying to authenticate the remains of a specimen from the Iron Age.

With some help from a homeless man, the Brennan and Booth search an abandoned tunnel system beneath Washington DC, hoping to solve the murder of a documentary filmmaker.

When a decomposed body is found in an alley, an investigation determines that the remains are those of an introverted teen who wrote comic books.

Booth and Brennan link two decomposed bodies to a street gang operating out of an El Salvadoran neighborhood… and to a United States Senator.

Brennan and Zach investigate a crash involving a State Department flight carrying Chinese diplomats; they find themselves drawn to bone fragments found near the crash site that belong to someone who could not have been on the flight.

Brennan is the target of a shooting, but it's not clear if the perpetrator is behind a recent serial killing or a six-year-old mob hit.

Brennan goes to New Orleans in order to aid in the identification of the bodies found in the aftermath of Hurricane Katrina, only to end up as the prime suspect in a murder of which she has no recollection.

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Brennan and Booth track the source of a young woman's lung cancer to a renegade company selling tainted bone grafts.

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When the remains of a Jane Doe turn out to be Brennan's mother, Brennan must face the truth of who her parents really were… and why they disappeared fifteen years ago.

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