Mac, Danny and Flack investigate the death of a medical intern and an illegal organ trafficking job at a hospital. Meanwhile, Stella and Lindsey look into the death of a young woman found with a bicycle spoke stuck in her neck.

When a patient from a mental hospital, who masquerades as Superman, is found dead in an alleyway Mac and Stella retrace his steps to find his murderer and restore justice to the city. Meanwhile, Danny and Lindsay find Tyrell Mann, A..K.A. Super Mann, a popular football star murdered in his luxurious hotel suite.

When an anonymous caller tells Mac there is a dead body buried at Giant’s Stadium, evidence found at the scene points to one of the CSIs. The team tries to crack the case and prove their investigator is innocent. Across, town Stella and Danny find a banker stabbed to death in his luxurious hotel suite.