When the CSI team is called to the Sphere Hotel to investigate a double homicide, they scour hotel’s security tapes for clues into who may be responsible for the murders. Meanwhile, Nick potentially jeopardizes the investigation by discussing specifics of the case, which later turn up on the local news -- giving the murderers insight into the investigation. Later, the team discovers another couple murdered in a similar fashion and they determine that they are looking for a serial killer.

Grissom is shocked to discover the prime suspects in his ongoing homicide investigation shot to death in their house. But what is more surprising is that their murder points to an inside job. Meanwhile, Catherine and Sara are called to investigate a college student found dead, floating in his shower.

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